BDBM386018 4-{4-[2-dimethylamino-1-(4-fluoro-phenyl)-ethyl]-piperazin-1-yl}-7,8-dihydro-5H-pteridin-6-one::US10287300, Compound A24

SMILES CN(C)CC(N1CCN(CC1)c1ncnc2NCC(=O)Nc12)c1ccc(F)cc1

InChI Key InChIKey=WCJGSTLAPOQOCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 386018   

TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM386018(4-{4-[2-dimethylamino-1-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent